Bono & Oprah made time for a picture at the “Project Red” campaign meeting in Chicago.

The famous U2 frontman & talk show host are trying to raise awareness as well as money to help fight AIDS in Africa.

You know, they kinda look like a natural couple.  Bono & Oprah sitting in a tree, k-i-s-s-i-n-g.  First comes love, then comes marriage, then comes Stedman in a baby carriage!