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Sluttypants Rose McGowan is being blamed with breaking up Grindhouse director Robert Rodriguez’s 16-year marriage.  Which surprises me not, anyone who would show up to an awards show wearing this with Marilyn Manson by her side is a little lost in the mental department.

McGowan & Rodriguez’s sexy time was infamous among the cast & crew of the movie, as the two would often have private “lunches” together in Robert’s trailer.

When Rodriquez’s wife (& mother to his five children) found out about the extramarital affair, she freaked out & left Robert where his greasy self stood.  Apparently filming for the double feature literally halted for a month as the director’s personal life fell apart.  

Rodriguez and his spouse of 16 years, Elizabeth Avellan, raised five kids and worked together, with Elizabeth serving as his co-producer on “Grindhouse,” “Sin City,” “From Dusk Till Dawn,” “Desperado” and “Spy Kids.”

But the marriage exploded last April when Page Six reported that Rodriguez, 38, had begun a torrid romance with McGowan, the raven-haired, French-Irish minx once engaged to shock rocker Marilyn Manson and previously linked with Kip Pardue, Ahmet Zappa and Men’s Health stud Dave Zinczenko.

“It was the worst-kept secret on the set. They were going off to his trailer, having meals together,” our source said. “Rose thought some of the crew were treating her differently, and the attitude was, like, well what do you expect when you’re [bleeping] the director?”

In “Grindhouse,” Rodriguez’s homage to the cheesy sex-and-violence movies of the 1970s, McGowan plays a stripper who loses her leg and replaces it with a machine gun to battle flesh-eating zombies.

She and Rodriguez first met at Cannes in 2005. But until now the consequences of their shenanigans weren’t fully known. When the director “fell in love with his femme-fatale star . . . he broke up his marriage of 16 years . . . The production had to shut down for a month while he recovered,” Variety reports.

Sluttypants McGowan, seems like that new nickname might be around for a bit, eh?

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